In theory, wheel bearings could last as long as your car. Unlike oil changes or tire rotations, there’s no standard maintenance schedule for replacing them. However, they can be damaged, especially if you hit a pothole, clip a curb or drive over a speed bump too fast. (And who hasn’t done that?)
If water, mud, road salt or sand get to the bearings, it will contaminate the grease in the hub assembly. In turn, the bearings will wear down, and eventually fail. In addition, ignoring worn-out wheel bearings can damage the vehicle’s inner or outer CV joints (constant velocity joints), which attaches to the driveshaft and transmission.
The best course of action? Find a reputable service technician for advice.