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Best Luxury Midsize Cars of 2022

Best Luxury Mid-Size Cars of 2022

Find the best luxury mid-size car of 2022 with our list by the Kelley Blue Book editors. They have driven and ranked each of these vehicles based on fuel economy, car value, technology, features, cargo space, safety, available options, driving performance, and more.

How we rate vehicles |
2022 Lexus ES
#1
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2022 Lexus ES

$32,339
Starting Price

4.8
rating
Expert Rating

28 MPG
Combined Fuel Economy
The 2022 Lexus ES premium midsize sedan is a winner on many levels. Undeniably luxurious, yet the most affordable car in its class.
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2022 Audi A7
#2
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$51,238
Starting Price

4.7
rating
Expert Rating

24 MPG
Combined Fuel Economy
The 2022 Audi A7 Sportback is a luxury midsize hatchback based on the A6 sedan, but with its own character, more power, and more equipment.

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2022 Mercedes-Benz E-Class
#2
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4.7
rating
Expert Rating

24 MPG
Combined Fuel Economy
The luxury 2022 Mercedes-Benz E-Class range covers midsize sedan, coupe, convertible and wagon variants, including powerful AMG versions.
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2022 BMW 5 Series
#4
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$34,068
Starting Price

4.5
rating
Expert Rating

28 MPG
Combined Fuel Economy
The 2022 BMW 5 Series is the premium midsize sedan for people who really like driving, yet still want luxury, technology, and space.
2022 Audi A6
#5
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$37,993
Starting Price

4.4
rating
Expert Rating

24 MPG
Combined Fuel Economy
The 2022 Audi A6 is a perfect premium midsize sedan. Size, style, equipment, tech, and driving talents are all in virtually ideal amounts.
2022 Genesis G80
#6
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$36,889
Starting Price

4.3
rating
Expert Rating

26 MPG
Combined Fuel Economy
The 2022 Genesis G80 luxury midsize sedan has moved beyond its original high-value premise to become a serious contender.
2022 Acura TLX
#7
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$28,518
Starting Price

4.2
rating
Expert Rating

24 MPG
Combined Fuel Economy
Whoever buys a 2022 Acura TLX will have a luxury compact sedan with a driver’s edge and a lot of standard equipment for a keen price.
2022 Volvo S90
#8
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$33,547
Starting Price

3.9
rating
Expert Rating

26 MPG
Combined Fuel Economy
The 2022 Volvo S90 is a luxury car worth considering if you prioritize safety, efficiency, and practicality in a premium midsize sedan.
2022 Cadillac CT5
#9
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$27,552
Starting Price

3.7
rating
Expert Rating

27 MPG
Combined Fuel Economy
The sleek 2022 Cadillac CT5 is a good value choice in midsize luxury sedans, but its relatively simple interior lags behind class leaders.
2022 Jaguar XF
#10
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$38,569
Starting Price

3.6
rating
Expert Rating

28 MPG
Combined Fuel Economy
The stylish Jaguar XF is a surprisingly good value for a sophisticated European midsize luxury sedan, but German rivals are more luxurious.
2022 Maserati Ghibli
#11
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3.3
rating
Expert Rating

16 MPG
Combined Fuel Economy
The Maserati Ghibli has exotic brand panache and the aesthetic to match, but almost all of its rivals are more luxurious at a lower price.
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What Our Ratings Mean

  • 0-1.0: This is the rarest group of all because a really bad new car is really, really hard to find these days. We recommend that you pass on any vehicle receiving a rating between 0 and 1.
  • 2.0: Cars landing in this set are also rare. Only true love and limitless passion (or a free vehicle) should allow you to give in to temptation for one of these vehicles.
  • 3.0: Is the vehicle you’re looking at in this range? We’d bet that if you look a little harder, you’ll find a better vehicle at a similar price to fulfill your needs.
  • 4.0: This is the area where the rubber meets the recommendations. The 3-4 range is full of good cars and some great ones. Starting here, it’s OK to listen to your heart.
  • 5.0: These scores represent the cream of the crop, with “5.0” representing, well, near perfection. Any car you choose in this group will treat you very well over time.

How Kelley Blue Book Rates Cars

Rather than pulling random numbers out of the air or off some meaningless checklist, KBB’s editors rank a vehicle to where it belongs in its class. Before any car earns its KBB rating, it must prove itself to be better (or worse) than the other cars it’s competing against as it tries to get you to spend your money buying or leasing.

Our editors drive and live with a given vehicle. We ask all the right questions about the interior, the exterior, the engine and powertrain, the ride and handling, the features, the comfort, and of course, about the price. Does it serve the purpose for which it was built? (Whether that purpose is commuting efficiently to and from work in the city, keeping your family safe, making you feel like you’ve made it to the top — or that you’re on your way — or making you feel like you’ve finally found just the right partner for your lifestyle.)

We take each vehicle we test through the mundane — parking, lane-changing, backing up, cargo space and loading — as well as the essential — acceleration, braking, handling, interior quiet and comfort, build quality, materials quality, reliability.

Meet our editors

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FAQ

What is the top-rated vehicle among best luxury midsize cars of 2022?

Currently, the 2022 Lexus ES tops the list of KBB.com’s best luxury midsize cars of 2022. After hours of test driving and analysis, our experts assigned the ES a rating of 4.8 out of 5 stars.

What are the top 3 vehicles among best luxury midsize cars of 2022?

The 2022 Lexus ES, 2022 Audi A7, and 2022 Mercedes-Benz E-Class are the highest-rated models on KBB.com’s list of best luxury midsize cars of 2022.

Which of the best luxury midsize cars of 2022 is the most affordable?

The 2022 Cadillac CT5 has a starting price of $27,552, making it the most affordable option on KBB.com’s list of best luxury midsize cars of 2022.

Which of the best luxury midsize cars of 2022 is the most fuel-efficient?

With a combined fuel economy of 28 MPG, the 2022 Jaguar XF is the most fuel-efficient vehicle on KBB.com’s list of the best luxury midsize cars of 2022.

What is the #1 best luxury midsize car of 2022 in America?

Currently the 2022 Lexus ES tops KBB's always up-to-date list of the best luxury midsize cars of 2022 in America. It gets 4.8 out of 5 stars from our car experts, has a starting MSRP of $32,339 and gets 28 MPG. Learn more at Kelley Blue Book.

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